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RheumaFinder is an AI-powered application that analyzes CT images for structural bone lesions of the sacroiliac joints

Developed for the opportunistic detection of structural lesions in CT studies performed for other clinical indications, without requiring additional imaging, RheumaFinder can detect structural bone lesions (erosion and ankylosis) in the sacroiliac joint region. Moreover, RheumaFinder can empower radiologists to identify patients with structural joint damage who otherwise would have never been flagged. Cloud native and PACS-agnostic, RheumaFinder will be implemented as an add-on application to any type of PACS, opening up new possibilities for higher diagnostic pickup rates and opportunistic detection and treatment of rheumatic disease with improved patient and societal outcomes.

RheumaFinder AI software integration with PACS for CT bone lesion detection
RheumaFinder software seamlessly integrates on any PACS
RheumaFinder AI software integration with PACS for CT bone lesion detection
RheumaFinder software
seamlessly integrates
on any PACS
RheumaFinder AI detecting structural bone lesions in sacroiliac joint CT scans
RheumaFinder software
has detected structural
bone lesions

Early opportunistic detection of structural lesions
in CT imaging

Artificial Intelligence (AI) can be used to detect structural bone lesions (erosion and ankylosis) in the sacroiliac joint region. In this way, more precise disease monitoring and follow-up is enabled, providing an extra layer of image interpretation and useful information.

Frequently, in medical images obtained for other diagnostic questions, incidental findings are present. Despite being detectable in the images, they are often not picked up due to their subtle appearance and foremost time constraints in the clinical practice. Preventive early detection of joint lesions can be achieved when the power of AI is used as an extra pair of eyes to support radiologists in the background.

AI is being used in radiology in a number of ways today. For the most effective use of AI, it is necessary to coordinate the input of high-quality expert-labelled medical images and algorithm development between physicians and computer scientists. These use cases can solve increasingly challenging problems in clinical practice. This (r)evolution in imaging depends on applying powerful AI tools to clinical problems in the best possible ways, i.e., the successful development of AI use cases.

Early opportunistic detection of structural lesions can prevent irreversible damage of the joints and disability thus improving quality of life

Developed for the opportunistic detection of structural lesions in CT studies, the RheumaFinder application is an AI-powered add-on to your PACS that may detect structural bone lesions (erosion and ankylosis) in the sacroiliac joint region. Moreover, it can detect inflammatory joint damage on CT images of the sacroiliac joints as incidental finding in examinations that are performed for other diagnostic questions.

The RheumaFinder software uses advanced AI to analyse CT images for structural bone lesions. In clinical validation, RFMapple 1 demonstrated a sensitivity of at least 70% and specificity of at least 90% for detecting joint erosion and ankylosis.

As cloud native solution, RheumaFinder will integrate the power, speed and flexibility of cloud computing. RheumaFinder will be implemented as an add-on to any type of PACS, quickly and easily. Available as a Software-as-a-Service, in a customer-tuned pay-per-use model, the efficacy of these algorithms in clinical practice is supported by significant scientific and clinical validation studies, fully compliant with GDPR and HIPAA privacy regulations.

AI highlighted findings of joint erosion and ankylosis on CT imaging
AI detected hallmark findings (structural lesions) are highlighted

Patient journey

Millions of people could get an earlier identification

As structural bone lesions are today not screened for and often remain undetected until irreversible major damage occurs, its early flagging will drastically improve the patient quality of life, reduce healthcare costs and improve decision making in the therapeutic journey.

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Important Regulatory Information
RFMapple is intended for use by qualified radiologists as a concurrent reading aid and is indicated for adults aged 18 to 60 years. RFMapple is a concurrent reading aid for radiologists. It is not intended as a standalone diagnostic device and does not replace clinical judgment.

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